








Position Summary
Position:
Department:
Medical Sciences Division
Institute:
University of Oxford
Country:
United Kingdom
Research Field:
chemical biology, chemistry
Posted Date:
NA
Deadline:
open until filled
Offer Period:
18 months
Offer Start Date:
NA
Postdoctoral Research Scientist in Bioconjugation Chemistry
Project Description:
We are seeking to appoint a Postdoctoral Research Scientist to join Professor Dame Molly Stevens’s laboratory at the Kavli Institute for Nanoscience Discovery, University of Oxford. The Stevens Group is based within the Department of Physiology, Anatomy and Genetics and is also affiliated with the Institute of Biomedical Engineering. We are looking for a talented bioconjugation chemist with broad expertise in the design and application of biomolecule ligation strategies for sensing and therapeutic applications.
The post holder will develop new chemical approaches for the site-specific labelling of biomolecules (such as proteins and peptides) to be integrated with next-generation sensing mechanisms. The role is highly multidisciplinary involving collaboration with researchers working within the fields of biochemistry, bioengineering, material science and biology. Successful candidates will engage with researchers both within the lab and across partner institutions, requiring strong organizational abilities and project management expertise to navigate complex, multi-team projects. The post-holder will be active within a vibrant and multidisciplinary environment comprising multiple research strands in fundamental and applied bionanoscience. Based at Prof. Molly Stevens’ group, the post will involve collaborations with other internationally recognised biomaterials and nanomaterials research groups. The Stevens Group has received numerous awards for outstanding biomaterials related research (www.stevensgroup.org) and comprises a diverse and multidisciplinary group of postdoctoral researchers and postgraduate students. We are looking for a talented scientist who is a confident self-starter and a collaborative team member with impeccable work ethics.
Responsibilities
- Design and implement new ligation methods for protein labelling applications, including sensing and therapeutics. • Carry out reagent synthesis for designed approaches.
- Perform bioconjugation reactions and subsequent characterisation and analysis with biomolecules (e.g., proteins and peptides).
- Establish cross-disciplinary protocols to incorporate the bioconjugation strategies into nextgeneration sensing and therapeutic applications with other members of the research team.
- Undertake the associated data analysis and interpretation, ensuring validity and reliability of data at all times.
- Help the other research staff in the daily management of the group laboratories.
- Liaise with the other research staff and students working in broad areas of relevance to the research project and partner institutions.
- Manage own academic research and administrative activities taking initiative in planning own research. This involves small scale project management, to co-ordinate multiple aspects of work to meet deadlines.
- Adapt existing and develop new scientific techniques and experimental protocols.
- Test hypotheses and analyse scientific data from a variety of sources, reviewing and refining working hypotheses as appropriate.
- Ensure compliance with Health and Safety (H&S) regulations and actively contribute to the development and implementation of best practices to promote a safe and efficient research environment.
- Contribute ideas for research projects across the group.
- Develop ideas for securing research funding, and present detailed research proposals to Prof. Stevens, management team and senior researchers.
- Collaborate in the preparation of scientific reports and journal articles and prepare material for presentation in oral and poster formats.
- Act as a source of information and advice to other members of the group on scientific protocols and experimental techniques.
- Represent the research group at external meetings/seminars, either with other members of the group or alone, for example by attending progress and management meetings as required and networking with the other research groups.
- Undertake instruction of PhD, masters and undergraduate students, as agreed.
- Prepare and deliver a small number of lectures and mark assessments, as agreed.
Other Duties
- Participate in a regular Annual Review;
- Undertake any necessary training identified and continuing professional development in order to stay up-to-date professionally including annual Information Governance training;
- Comply with Health and safety regulations;
- Comply with the policies and procedures set out in the Handbook for University Support staff (or) Academic-Related staff;
- Any other duties that may be required from time to time commensurate with the grade of the job.
Required Qualification:
Essential Qualification:
- Hold, or be near to completion of, a PhD/DPhil in chemical biology, chemistry, or related field.
- Experience in techniques including organic synthesis and peptide/protein chemistry.
- Experience in performing bioconjugation reactions and characterising bioconjugates.
- Previous experience of contributing to publications/presentations, with a proven track record of first author publications in peer reviewed journals.
- Excellent communication skills, including the ability to write for publication, present research proposals and results, and represent the research group at meetings.
- Ability to manage own academic research and associated activities.
- Knowledge of laboratory health and safety regulations and experience in implementation of best practices.
- Commitment to engaging with, and promoting awareness of, equality, diversity and inclusion and embedding these into your work.
Preferred Qualification:
- Experience in analysis of bioconjugates (e.g., protein fragments, peptides, proteins), including by LCMS, SDS-PAGE, HPLC.
- Experience in multi-step organic synthesis.
- Experience in site-selective biomolecule and nucleic acid modification.
- Experience in cross-team collaborative research, including effective project management, adherence to tight deadlines, and technical reporting.
- An interest in clinical translation of science.
- Experience working in a multidisciplinary research environment.
- Experience of independently managing a discrete area of a research project.
- Experience of actively collaborating in the development of research funding applications.
Employment Conditions and Benefits:
Contract duration:
- 18 months
Benefits:
- Grade 7: £39,424 - £47,779 per annum
Application Process:
Documents Required:
Not Available
How to apply:
https://my.corehr.com/pls/uoxrecruit/erq_jobspec_version_4.display_form?p_company=10&p_internal_external=E&p_display_in_irish=N&p_process_type=&p_applicant_no=&p_form_profile_detail=&p_display_apply_ind=Y&p_refresh_search=Y&p_recruitment_id=184042
About the Host Lab Group/Institution:
Welcome to the University of Oxford. We aim to lead the world in research and education for the benefit of society both in the UK and globally. Oxford’s researchers engage with academic, commercial and cultural partners across the world to stimulate high-quality research and enable innovation through a broad range of social, policy and economic impacts. We believe our strengths lie both in empowering individuals and teams to address fundamental questions of global significance, while providing all our staff with a welcoming and inclusive workplace that enables everyone to develop and do their best work. Recognising that diversity is our strength, vital for innovation and creativity, we aspire to build a truly diverse community which values and respects every individual’s unique contribution. While we have long traditions of scholarship, we are also forward-looking, creative and cutting-edge. Oxford is one of Europe's most entrepreneurial universities and we rank first in the UK for university spinouts, and in recent years we have spun out 15-20 new companies every year. We are also recognised as leaders in support for social enterprise. Join us and you will find a unique, democratic and international community, a great range of staff benefits and access to a vibrant array of cultural activities in the beautiful city of Oxford. For more information, please visit www.ox.ac.uk/about/organisation.
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Frequently Asked Questions:
Who can apply for a postdoctoral position?
Postdoctoral positions are open to candidates who have completed a PhD or will complete their doctoral degree before the start date. Eligibility requirements may vary depending on the funding scheme and host institution.
Can international candidates apply?
Yes. Most postdoctoral positions are open to international applicants. Visa sponsorship and work permit support are usually provided by the host institution, subject to local regulations.
Is prior postdoctoral experience required?
In most cases, prior postdoctoral experience is not mandatory. However, candidates with relevant research experience beyond the PhD may be preferred for certain positions.
What is the typical duration of a postdoctoral contract?
Postdoctoral contracts typically range from six months to three years, with the possibility of extension depending on funding availability and performance.
Are teaching responsibilities included?
Teaching responsibilities vary by institution and position. Some postdoctoral roles are research-only, while others may include limited teaching or supervision duties.
Can I apply for multiple postdoctoral positions?
Yes. Candidates are encouraged to apply for multiple suitable postdoctoral positions to increase their chances of selection.
Disclaimer:
This position is published for informational purposes. Please refer to the official application link for the most accurate and up-to-date details.